Ukwehlisa i-low-density lipoprotein cholesterol (LDL-C) kuyisu eliwumgogodla ekuvimbeleni nasekwelapheni izifo zenhliziyo. I-Earthworm fibrinolytic enzyme, i-enzyme enamandla ye-fibrinolytic, ifakazelwe ukuthi ikhombisa ukusebenza ngempumelelo ekwehliseni i-LDL-C nasekuthuthukiseni impilo yemithambo."OKUBILI"FhlehlisaDryersusa kahle umswakama, unciphise ukuwohloka kwe-enzyme nokungasebenzi, ngaleyo ndlela andise impilo yeshalofu. Ngaphezu kwalokho, ngokuya nge-bioavailability, ukomisa iqhwa kusiza ukugcina umsebenzi we-enzyme, kuthuthukisa ukuncibilika, futhi kuthuthukisa ukumuncwa kanye nokusetshenziswa emzimbeni. Lokhu kukhulisa kakhulu imiphumela yayo yokwehlisa i-LDL-C.
Ⅰ.Ukusetshenziswa Kobuchwepheshe Bokumisa Iqhwa Ekulungiseleleni I-Earthworm Fibrinolytic Enzyme Lyophilized Powder
Ukomisa iqhwa, okwaziwa nangokuthi i-lyophilization, kuyinqubo esusa umswakama ezintweni kusetshenziswa imishini yokomisa iqhwa ukuze kugcinwe ukwakheka nokusebenza kwazo. Ukulungiswa kwe-enzayimu ye-eyezophilized enzyme ye-earthworm fibrinolytic kuhilela izinyathelo ezimbili eziyinhloko: ukuqandisa nokumisa nge-vacuum. Le nqubo isusa ngempumelelo umswakama ophuma ku-enzyme ngenkathi igcina umsebenzi wayo webhayoloji nokuzinza.
Ⅱ.Ukutshala Izinhlobo Ezisezingeni Eliphezulu
Ukukhetha izinhlobo ezinesivuno esikhulu sokukhiqiza ama-enzyme kubalulekile empumelelweni yenqubo yokukhiqiza. Ngokuhlolwa nokuthuthukiswa, izinhlobonhlobo ezinomsebenzi ophezulu kanye nokukhiqiza ziyatshalwa ukuze kuthuthukiswe umthamo wokukhiqiza ama-enzyme.
Ⅲ.Ukukhipha kanye Nokuhlanzwa
Ubuchwepheshe bokukhipha obuthuthukisiwe busetshenziswa ukuhlukanisa i-enzayimu ye-earthworm fibrinolytic kusuka ezinhlobonhlobo, kulandelwa ukuhlanzwa ukuze kukhishwe ukungcola. Izindlela ezijwayelekile zifaka ukuphazamiseka kwe-ultrasonic, i-centrifugation, kanye nekholomu ye-chromatography, enikeza ukukhishwa kwe-enzyme ehlanzekile.
Ⅳ.Inqubo Yokumisa Yiqhwa
Ukusebenzisa"OKUBILI"FhlehlisaDryerimishini, i-enzyme ekhishwe icutshungulwa ibe yimpushana ye-lyophilized ezinzile. Phakathi nenqubo yokumisa iqhwa, amapharamitha afana namazinga okushisa namazinga e-vacuum ayalungiswa ukuze kuqinisekiswe ukuthi umsebenzi we-enzyme nokuzinza kuyagcinwa.
Ⅴ.Izinzuzo ze-Freeze-Dryer Technology
"KOKUBILI" ubuchwepheshe bokomisa iqhwa bunikeza izinzuzo ezilandelayo ekuthuthukiseni ukuzinza kanye nokuba khona kwe-bioavailability ye-enzayimu ye-earthworm fibrinolytic i-lyophilized powder:
Ⅵ.Ubuchwepheshe Bokuqandisa Okuthuthukisiwe
Ubuchwepheshe bokuqandisa obusanda kuklanywa obungu-50°C bumisa ngokushesha ukukhishwa kwe-enzyme, kuvimbele ukwakheka kwekristalu nokushintshashintsha kwezinga lokushisa okungafaka engozini umsebenzi we-enzyme.
Ⅶ.Precise Drying Control
I-"BOTH" i-freeze-dryer inesistimu yokulawula ukomisa enembile, evumela izinga lokushisa (-50°C ukuya ku-+45°C) nokulungiswa kwe-vacuum (1–30 Pa) ngokusekelwe ezidingweni zenqubo. Lokhu kuqinisekisa ukuzinza nokusebenza kwe-enzyme ngesikhathi somiswa.
Ⅷ.Ukuhlaziywa Kwemiphumela Yokunciphisa I-LDL-C
I-Lyophilized earthworm fibrinolytic enzyme ecutshungulwe ngobuchwepheshe be-freeze-dryer igcina umsebenzi ophezulu webhayoloji. Izivivinyo zomtholampilo zibonisa ukuthi umphumela wayo wokwehlisa i-LDL-C udlula ngokuphawulekayo lowo wama-enzyme acutshungulwa ngokujwayelekile. Izici ezibalulekile zifaka:
1.I-Enhanced Solubility: I-lyophilized powder incibilika ngokushesha emanzini, ikhulula izingxenye ezisebenzayo futhi ithuthukise ukumuncwa nokusetshenziswa emzimbeni.
2.Ukugcinwa Komsebenzi: Inqubo yokumisa iqhwa inciphisa ukungasebenzi kwe-enzyme, ivumela ukuthi isebenze isikhathi eside emzimbeni futhi ithuthukise ukusebenza kahle kokunciphisa i-LDL-C.
Ukusetshenziswa kobuchwepheshe bokumisa iqhwa ekulungiseleleni i-enzayimu ye-eyenziyophilized ye-eyenziyophilized igcina umsebenzi we-enzyme nokuzinza ngenkathi ithuthukisa ukutholakala kwe-bioavailability. Lokhu kunikeza ukwakheka kwezidakamizwa okusebenzayo kokwehlisa i-LDL-C kanye nokwenza ngcono impilo yemithambo. Ngokuthuthuka okuqhubekayo kubuchwepheshe bokumisa iqhwa, ukusetshenziswa okusabalele kwe-"BOTH" okomisa okomisa ekukhiqizeni i-enzyme powder kunikeza izixazululo ezintsha zokuvimbela nokwelashwa kwezifo zenhliziyo nemithambo yegazi.
Uma unentshisekelo yethuUmshini Wokomisa Iqhwanoma unemibuzo, sicela ukhululekeXhumana nathi. Njengomkhiqizi ochwepheshile womshini wokomisa umshini wokuqandisa, sinikeza imininingwane ehlukahlukene, efaka phakathi okwasendlini, ilabhorethri, umshayeli wendiza, namamodeli okukhiqiza. Noma ngabe udinga okokusebenza okuzosetshenziswa ekhaya noma okokusebenza kwezimboni ezinkulu, singakuhlinzeka ngemikhiqizo namasevisi ekhwalithi ephezulu kakhulu.
Isikhathi sokuthumela: Jan-13-2025